Connecting Data to Accelerate Cancer Research

The NCI Cancer Research Data Commons (CRDC) is a cloud-based data science infrastructure that provides secure access to a large, comprehensive, and expanding collection of cancer research data. Users can explore and use analytical and visualization tools for data analysis in the cloud.

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134K+ Subjects / Participants 10PB+ Data 354 Studies 2K+ Public Tools and Workflows 82.3K+ Unique Users / Year
354 Studies 134K+ Subjects / Participants 2K+ Public Tools and Workflows 82.3K+ Unique Users / Year 10PB+ Data
  • CRDC Insights
    CRDC Components: Updates

    The CRDC team, whether engaged in activities specific to the CRDC Data Commons, NCI Cloud Resources, or CRDC’s Core Services, remains focused on advancing its mission of making data and resources securely accessible to the cancer research community. The team has provided updates. Read more below.

  • CRDC Insights
    CRDC at the 2025 AACR Annual Meeting

    Members of the CRDC team engaged with the cancer research community at the 2025 AACR Annual Meeting through collaborative sessions and posters. Ina Felau, MS, presented in a joint session with colleagues from the NCI Office of Data Sharing (ODS) on “Enhancing FAIR Sharing and Reuse of Cancer Research Data.”

     

     

  • CRDC Insights
    How CRDC Resources are Used

    Several members of the CRDC team recently published an assessment of publications that reference CRDC-housed data and/or the use of NCI Cloud Resources and the analytical tools CRDC makes publicly available. The paper titled, “Usage of the National Cancer Institute Cancer Research Data Commons by Researchers: A Scoping Review of the Literature

  • CRDC Insights
    CRDC Components: Updates

    The CRDC team, whether engaged in activities specific to the CRDC Data Commons, NCI Cloud Resources, or CRDC’s Core Services, remains focused on advancing its mission of making data and resources securely accessible to the cancer research community. The team has provided updates. Read more below.

  • CRDC Insights
    CRDC at the 2025 AACR Annual Meeting

    Members of the CRDC team engaged with the cancer research community at the 2025 AACR Annual Meeting through collaborative sessions and posters. Ina Felau, MS, presented in a joint session with colleagues from the NCI Office of Data Sharing (ODS) on “Enhancing FAIR Sharing and Reuse of Cancer Research Data.”

     

     

  • CRDC Insights
    How CRDC Resources are Used

    Several members of the CRDC team recently published an assessment of publications that reference CRDC-housed data and/or the use of NCI Cloud Resources and the analytical tools CRDC makes publicly available. The paper titled, “Usage of the National Cancer Institute Cancer Research Data Commons by Researchers: A Scoping Review of the Literature

Explore

Data Commons

Genomic Data Commons (GDC)

Share, analyze, and visualize harmonized genomic data, including TCGA, TARGET, and CPTAC.

Proteomic Data Commons (PDC)

Share, analyze, and visualize proteomic data, such as CPTAC and The International Cancer Proteogenome Consortium (ICPC).

Imaging Data Commons (IDC)

Share, analyze, and visualize multi-modal imaging data from both clinical and basic cancer research studies.

Integrated Canine Data Commons (ICDC)

Share data from canine clinical trials, including the PRE-medical Cancer Immunotherapy Network Canine Trials (PRECINCT) and the Comparative Oncology Program.

Clinical and Translational Data Commons (CTDC)

Store and share data from NCI-funded Clinical and Translational Studies.

General Commons (GC)

Hosting and sharing NCI data of multiple data types not a match for other CRDC Data Commons.

Core Standards and Services

Cancer Data Aggregator (CDA)

Enables users to query and connect data distributed across the CRDC for integrative analysis.

Data Standards Services (DSS)

Provides services to facilitate interoperability of data across CRDC.

Data Commons Framework (DCF)

Provides secure user authentication and authorization and permanent digital object identifiers for data objects.

Cloud Resources

Broad Institute FireCloud

Access NCI-funded datasets TARGET and TCGA along with a rich collection of other datasets and collaborative projects that are part of the biomedical ecosystem. Run analysis tools at scale and collaborate securely on a scalable cloud environment.

Seven Bridges Cancer Genomics Cloud developed by Velsera (SB-CGC)

Explore and analyze large datasets alongside secure and scalable analytical resources for large-scale computational research.

ISB Cancer Gateway in the Cloud (ISB-CGC)

Access data sets using fully interactive web-based applications, including BigQuery, which is hosted on Google Cloud Platform.

ABOUT CRDC

CRDC is built for researchers

  • Enable the cancer research community to share diverse data types
  • Provide secure access to data
  • Facilitate the generation of innovative tools
  • Adhere to FAIR principles of data stewardship: Findable, Accessible, Interoperable, and Reusable