Select Publications

CRDC lists peer-reviewed publications that showcase the breadth and depth of research using CRDC data and resources.

TitleJournalPublication DateCRDC Component
Comparative Analysis of Distinct Genomic Landscapes in Young-Onset gBRCA1/2 Breast CancerJCI Insight4/28/2026GDC
Pan-cancer Analysis and Experimental Validation Identify CYP19A1 as a Prognostic Biomarker and Oncogenic Driver Associated with Tumor Immune Microenvironment Regulation in Gastrointestinal CancersDiscover Oncology4/27/2026GDC
Enhancer and Metabolic Rewiring by KMT2C-COMPASS or KMT2D-COMPASS Family Loss in Cancer Creates Druggable VulnerabilitiesNature Reviews Cancer4/24/2026GDC
Analysis of Ovarian Cancer Immune Cell Profiles Associated with Clinical OutcomesPLOS One4/20/2026GDC
Coherent Cross-Modal Generation of Synthetic Biomedical Data to Advance Multimodal Precision MedicinePLOS Computational Biology4/16/2026GDC
Systematic Pan-Cancer Characterization of ST3GAL4 Reveals Its Prognostic and Immunologic AssociationsBiomedicines3/27/2026GDC
Investigation of Angiogenesis and Epithelial-Mesenchymal Transition Markers in Prostatic Cancer PatientsWorld Journal of Surgical Oncology3/25/2026GDC
Proteogenomic Analysis of Gastrointestinal DiseaseGut1/29/2026PDC
MOKCa-3D Database: Functional and Structural Analysis of Missense Mutations in CancerDatabase1/15/2026GDC
Integrative Analysis Of Lung Adenocarcinoma Across Diverse Ethnicities And Exposures Cancer Cell9/8/2025PDC
Proteomic-Based Stemness Score Measures Oncogenic Dedifferentiation And Enables The Identification Of Druggable Targets Cell Genomics6/11/2025PDC
Three-Dimensional Genome Landscape of Primary Human Cancers Nature Genetics5/12/2025GDC
DNA Methylation Epitypes of Burkitt Lymphoma with Distinct Molecular and Clinical Features Blood Cancer Discovery5/8/2025GDC
Precision Proteogenomics Reveals Pan-Cancer Impact Of Germline Variants Cell5/1/2025PDC
Integrated Multi-omics Analyses of Oral Squamous Cell Carcinoma Reveal Precision Patient Stratification and Personalized Treatment Strategies Cancer Letters4/1/2025PDC
Deciphering The Dark Cancer Phosphoproteome Using Machine-Learned Co-Regulation Of Phosphosites Nature Communications3/20/2025PDC
Proteogenomic Characterization of Molecular and Cellular Targets for Treatment-Resistant Subtypes in Locally Advanced Cervical Cancers Molecular Cancer3/14/2025PDC
Classification of non-TCGA Cancer Samples to TCGA Molecular Subtypes Using Compact Feature SetsCancer Cell2/10/2025GDC
Unlocking the Potential of Digital Pathology: Novel Baselines for CompressionJournal of Pathology Informatics12/28/2024IDC
Mapping The Functional Network Of Human Cancer Through Machine Learning And Pan-Cancer Proteogenomics Nat Cancer12/11/2024PDC
Genomic Determinants of Outcome in Acute Lymphoblastic Leukemia Journal of Clinical Oncology10/10/2024GDC
Proteogenomic Insights Suggest Druggable Pathways in Endometrial CarcinomaCancer Cell9/11/2024PDC
Single-Cell Chromatin Accessibility Reveals Malignant Regulatory Programs in Primary Human CancersScience9/6/2024GDC
Multiomics2Targets Identifies Targets From Cancer Cohorts Profiled With Transcriptomics, Proteomics, And Phosphoproteomics Cell Reports Methods8/19/2024PDC
Pan-Cancer Proteogenomics Expands The Landscape Of Therapeutic Targets Cell8/8/2024PDC
Illuminating Key Signaling Pathways and Tumor Evolution in High-Grade GliomaCancer Cell7/16/2024PDC
Multi-Scale Signaling And Tumor Evolution In High-Grade Gliomas Cancer Cell7/8/2024PDC
Multi-Omic Profiling Of Intraductal Papillary Neoplasms Of The Pancreas Reveals Distinct Expression Patterns And Potential Markers Of Progression bioRxiv7/7/2024PDC
Comprehensive Proteogenomic Characterization of Rare Kidney TumorsCell Reports Medicine5/21/2024PDC
NCI Cancer Research Data Commons: Lessons Learned and Future StateCancer Research5/02/2024CRDC
NCI Cancer Research Data Commons: Resources to Share Key Cancer DataCancer Research5/02/2024CRDC
NCI Cancer Research Data Commons: Cloud-Based Analytic ResourcesCancer Research5/02/2024FC, ISB-CGC, SB-CGC
NCI Cancer Research Data Commons: Core Standards and ServicesCancer Research5/02/2024CRDC
Proteogenomic Analysis of Enriched HGSOC Tumor Epithelium Identifies Prognostic Signatures and Therapeutic VulnerabilitiesNPJ Precision Oncology3/13/2024GDC
Integrated Proteogenomic Characterization of Glioblastoma EvolutionCancer Cell3/11/2024PDC
Pan-Cancer Proteogenomics Characterization Of Tumor Immunity Cell2/29/2024PDC
Frozen Tissue Coring and Layered Histological Analysis Improves Cell Type-Specific Proteogenomic Characterization of Pancreatic AdenocarcinomaClinical Proteomics1/30/2024PDC
Enrichment of Lung Cancer Computed Tomography Collections with AI-Derived AnnotationsNature Scientific Data1/24/2024IDC
Mapping the Proteogenomic Landscape Enables Prediction of Drug Response in Acute Myeloid LeukemiaCell Reports Medicine1/16/2024PDC
Detection of Pancreatic Ductal Adenocarcinoma-Associated Proteins in SerumMolecular and Cellular Proteomics1/2024PDC
Leading the Pack: Best Practices in Comparative Canine Cancer Genomics to Inform Human OncologyVeterinary and Comparative Oncology12/2023ICDC
The NCI Imaging Data Commons as a Platform for Reproducible Research in Computational PathologyComputer Methods and Programs in Biomedicine12/2023IDC
National Cancer Institute Imaging Data Commons: Toward Transparency, Reproducibility, and Scalability in Imaging Artificial IntelligenceRadioGraphics11/24/2023IDC
Idppub: Illuminating The Dark Phosphoproteome Through Pubmed Mining Molecular & Cellular Proteomics11/21/2023PDC
A Proteogenomics Data-Driven Knowledge Base of Human Cancer Cell Systems9/20/2023PDC
Integrative Multi-Omic Cancer Profiling Reveals DNA Methylation Patterns Associated with Therapeutic Vulnerability and Cell-of-OriginCancer Cell9/11/2023PDC
Pan-Cancer Proteogenomics Connects Oncogenic Drivers to Functional StatesCell8/14/2023PDC
Deep Learning Integrates Histopathology and Proteogenomics at a Pan-Cancer LevelCell Reports Medicine8/14/2023PDC
Pan-Cancer Analysis of Post-Translational Modifications Reveals Shared Patterns of Protein RegulationCell8/14/2023PDC
Proteogenomic Data and Resources for Pan-Cancer AnalysisCancer Cell8/14/2023PDC
Proteogenomic Analysis Of Chemo-Refractory High-Grade Serous Ovarian Cancer Cell8/3/2023PDC
Transparent and Reproducible AI-based Medical Imaging Pipelines Using the CloudResearch Square7/21/2023IDC
Enrichment of the NLST and NSCLC-Radiomics Computed Tomography Collections with AI-Derived AnnotationsArXiv5/21/2023IDC
Integrated Glycoproteomic Characterization of Clear Cell Renal Cell CarcinomaCell Reports Medicine4/18/2023PDC
Interoperable Slide Microscopy Viewer and Annotation Tool for Imaging Data Science and Computational PathologyNature Communications3/22/2023IDC
Refining Classification Of Cholangiocarcinoma Subtypes Via Proteogenomic Integration Reveals New Therapeutic Prospects Gastroenterology3/9/2023PDC
Proteogenomic Landscape of Human Pancreatic Ductal Adenocarcinoma in an Asian Population Reveals Tumor Cell-Enriched and Immune-Rich SubtypesNature Cancer12/22/2022PDC
Histopathologic and Proteogenomic Heterogeneity Reveals Features of Clear Cell Renal Cell Carcinoma AggressivenessCancer Cell12/22/2022PDC
Proteogenomic Analysis of Lung Adenocarcinoma Reveals Tumor Heterogeneity, Survival Determinants, and Therapeutically Relevant PathwaysCell Reports Medicine11/15/2022PDC, GDC
Proteogenomic Analysis Of Lung Adenocarcinoma Reveals Tumor Heterogeneity, Survival Determinants And Therapeutically-Relevant Pathways Cell Reports Med11/15/2022GDC, PDC
Proteogenomic Markers of Chemotherapy Resistance and Response in Triple Negative Breast CancerCancer Discovery11/2/2022PDC
Neoplastic Cell Enrichment of Tumor Tissues Using Coring and Laser Microdissection for Proteomic and Genomic Analyses of Pancreatic Ductal AdenocarcinomaClinical Proteomics10/20/2022PDC
Genetic Subgroups Inform on Pathobiology in Adult and Pediatric Burkitt LymphomaBlood10/6/2022GDC
Integrated Stem Cell Signature And Cytomolecular Risk Determination In Pediatric Acute Myeloid Leukemia Nature Communications9/19/2022GDC
The Genomic Landscape of Pediatric Acute Lymphoblastic LeukemiaNature Genetics9/01/2022GDC
Highdicom: a Python Library for Standardized Encoding of Image Annotations and Machine Learning Model Outputs in Pathology and RadiologyJournal of Digital Imaging8/22/2022IDC
Integrative Analysis of Drug Response and Clinical Outcome in Acute Myeloid LeukemiaCancer Cell8/8/2022GDC
Proteomic and Phosphoproteomic Measurements Enhance Ability to Predict Ex Vivo Drug Response in AMLClinical Proteomics7/27/2022PDC
Genetic Changes Associated with Relapse in Favorable Histology Wilms tumor: A Children's Oncology Group AREN03B2 StudyCell Reports Medicine6/21/2022GDC
Genetic Changes Associated With Relapse In Favorable Histology Wilms Tumor - A Children’S Oncology Group Aren03B2 Study Cell Reports Medicine6/21/2022GDC
Combinatorial and Machine Learning Approaches for Improved Somatic Variant Calling from Formalin-Fixed Paraffin-Embedded Genome Sequence DataFrontiers in Genetics4/27/2022GDC
The AIMI Initiative: AI-Generated Annotations for Imaging Data Commons CollectionsArXiv11/21/2021IDC
Transcriptomic Profiling in Canines and Humans Reveals Cancer Specific Gene Modules and Biological Mechanisms Common to Both SpeciesPLOS Computational Biology9/27/2021ICDC
Proteogenomic Characterization of Pancreatic Ductal AdenocarcinomaCell9/16/2021PDC
NCI Imaging Data CommonsCancer Research8/15/2021IDC
A Proteogenomic Portrait of Lung Squamous Cell CarcinomaCell8/5/2021PDC
Canine Tumor Mutational Burden is Correlated with TP53 Mutation Across Tumor Types and BreedsNature Communications8/3/2021ICDC
The AML Microenvironment Catalyzes a Step-Wise Evolution to Gilteritinib ResistanceCancer Cell6/24/2021PDC
Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 DogsAACR6/1/2021ICDC
Lack Of Transgenerational Effects Of Ionizing Radiation Exposure In Cleanup Workers And Evacuees Of The Chernobyl Accident Science5/14/2021GDC
Radiation-Related Genomic Profile Of Papillary Thyroid Cancer After The Chernobyl Accident Science5/14/2021GDC
Reliable Analysis of Clinical Tumor-Only Whole-Exome Sequencing DataJCO Clin Cancer Inform4/13/2021Broad - FireCloud 
Proteogenomic and Metabolomic Characterization of Human GlioblastomaCancer Cell4/12/2021PDC
Proteogenomic Insights into the Biology and Treatment of HPV-Negative Head and Neck Squamous Cell CarcinomaCancer Cell3/8/2021PDC
RNA Splicing and Aggregate Gene Expression Differences in Lung Squamous Cell Carcinoma Between Patients of West African and European AncestryLung Cancer3/1/2021GDC
Whole-Genome Characterization Of Lung Adenocarcinomas Lacking Alterations In The Rtk/Ras/Raf Pathway Cell Reports2/23/2021GDC
Bringing Structural Implications and Deep Learning-Based Drug Identification for KRAS MutantsJ Chem Inf Model2/22/2021GDC
The NCI Genomic Data CommonsNature Genetics2/22/2021GDC
Uniform Genomic Data Analysis in the NCI Genomic Data CommonsNature Communications2/22/2021GDC
TAp73β Can Promote Hepatocellular Carcinoma DedifferentiationCancers (Basel)2/13/2021GDC
Genotyping Common, Large Structural Variations in 5,202 Genomes Using Pangenomes, the Giraffe Mapper, and the VG ToolkitbioRxiv2/2/2021Broad - FireCloud 
A cross-disorder dosage sensitivity map of the human genomemedRxiv1/28/2021Broad - FireCloud 
Expression and Gene Regulatory Network of SNHG1 in Hepatocellular CarcinomaBMC Med Genomics1/26/2021GDC
Assessing single-cell transcriptomic variability through density-preserving data visualizationNature Biotechnology 1/18/2021Broad - FireCloud 
Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost powerNature Genetics 1/18/2021Broad - FireCloud 
Streamlining data-intensive biology with workflow systemsGigaScience1/13/2021Broad - FireCloud 
BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportionMedRxiv1/9/2021Broad - FireCloud 
Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain CancerCell12/23/2020PDC
The first insight into the genetic structure of the population of modern SerbiabioRxiv12/18/2020SB-CGC
Ace2 expression is higher in intestines and liver while being tightly regulated in development and disease in zebrafishbioRxiv12/14/2020SB-CGC
Metabolism-Associated Molecular Classification of Colorectal CancerFront Oncol12/4/2020GDC
Genomic and epigenetic aberrations of chromosome 1p36.13 have prognostic implications in malignanciesChromosome Res12/1/2020GDC
Transcriptional Landscape of Hepatocellular Carcinoma Reveals that Patient Ethnic-Origin Influences Patterns of ExpressionbioRxiv12/1/2020SB-CGC
Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted TherapyCell11/25/2020PDC
Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cellsRNA Biology11/17/2020SB-CGC
Strengthening the BioCompute Standard by Crowdsourcing on PrecisionFDAbioRxiv11/2/2020SB-CGC
Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian CarcinomaCell Reports Medicine10/20/2020PDC
Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancersOncogene10/14/2020SB-CGC
Alzheimer Gene BIN1 may Simultaneously Influence Dementia Risk and Androgen Deprivation Therapy Dosage in Prostate CancerAm J Clin Oncol10/1/2020GDC
BCO App: tools for generating BioCompute Objects from next-generation sequencing workflows and computationsF1000Research9/16/2020SB-CGC
OpenGDC: Unifying, Modeling, Integrating Cancer Genomic Data and Clinical MetadataApplied Sciences9/12/2020SB-CGC
Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell TumorsMethods Mol Biol8/28/2020GDC
Integrated Analysis of Germ Cell TumorsTesticular Germ Cell Tumors8/28/2020Broad - FireCloud 
The Veterans Affairs Precision Oncology Data Repository, a Clinical, Genomic, and Imaging Research DatabasePatterns (N Y)8/17/2020GDC
Analysis Of Ugandan Cervical Carcinomas Identifies Human Papillomavirus Clade-Specific Epigenome And Transcriptome Landscapes Nature Genetics8/3/2020GDC
Linked Entity Attribute Pair (LEAP): A Harmonization Framework for Data PoolingJCO Clin Cancer Inform8/1/2020GDC
Scalability and cost-effectiveness analysis of whole genome-wide association studies on Google Cloud Platform and Amazon Web ServicesJ am Med Inform Assoc.7/27/2020SB-CGC
Proteogenomic characterization of human colon and rectal cancerNature7/20/2020PDC
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma.Cell7/9/2020PDC
Proteogenomics of Non-smoking Lung Cancer in East Asia Delineates Molecular Signatures of Pathogenesis and Progression.Cell7/9/2020PDC
Proteogenomic Characterization Reveals Therapeutic Vulnerabilities In Lung Adenocarcinoma Cell7/9/2020PDC
Proteogenomics Of Non-Smoking Lung Cancer In East Asia Delineates Molecular Signatures Of Pathogenesis And Progression Cell7/9/2020PDC
Oncogenic Features in Histologically Normal Mucosa: Novel Insights Into Field Effect From a Mega-Analysis of Colorectal TranscriptomesClin Transl Gastroenterol7/1/2020GDC
LINE-1 expression in cancer correlates with DNA damage response, copy number variation, and cell cycle progressionbioRxiv6/28/2020SB-CGC
Type 3 innate lymphoid cells are associated with a successful intestinal transplantAm J Transplant6/28/2020SB-CGC
Identification of the key genes and characterizations of Tumor Immune Microenvironment in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC)J Cancer6/16/2020GDC
Identification of an Immune Score-Based Gene Panel with Prognostic Power for Oral Squamous Cell CarcinomaMed Sci Monit6/12/2020GDC
Classification and mutation prediction based on histopathology H&E images in liver cancer using deep learningNPJ Precis Oncol6/8/2020GDC
The road towards data integration in human genomics: players, steps and interactionsBrief Bioinform6/4/2020SB-CGC
AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2Nat Commun.6/2/2020SB-CGC
Increased number of subclones in lung squamous cell carcinoma elicits overexpression of immune related genesTransl Lung Cancer Res6/1/2020GDC
Measuring Cancer Hallmark Mediation of the TET1 Glioma Survival Effect with Linked Neural-Network Based Mediation ExperimentsSci Rep6/1/2020GDC
Modern Information Technology for Cancer Research: What’s in IT for Me? An Overview of Technologies and ApproachesOncology6/1/2020SB-CGC
Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and AnalysisCancer Research6/1/2020SB-CGC
A structural variation reference for medical and population geneticsNature5/27/2020Broad - FireCloud 
Implementing the FAIR Data Principles in precision oncology: review of supporting initiativesBrief Bioinform5/21/2020GDC
An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypesMol Med5/20/2020GDC
Comprehensive Analysis Of Genetic Ancestry And Its Molecular Correlates In Cancer Cancer Cell5/11/2020GDC
Co-occurrent Alterations of Alzheimer's Genes and Prostate Cancer Genes in Prostate CancerCancer Genomics Proteomics5/1/2020GDC
Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability.Cell Reports Medicine4/21/2020PDC
Proteogenomic Characterization Of Ovarian Hgsc Implicates Mitotic Kinases, Replication Stress In Observed Chromosomal Instability Cell Reports Med4/21/2020PDC
Open Health Imaging Foundation Viewer: An Extensible Open-Source Framework for Building Web-Based Imaging Applications to Support Cancer ResearchJCO Clin Cancer Inform4/4/2020ISB-CGC
Automatic Staging of Cancer Tumors Using AIM Image Annotations and OntologiesJ Digit Imaging4/1/2020GDC
Whole Exome Sequencing Data Analysis Algorithms in Cancer DiagnosticsPrime Archives of Cancer Research3/27/2020SB-CGC
Deep Proteomics Using Two Dimensional Data Independent Acquisition Mass Spectrometry Analytical Chemistry3/17/2020PDC
Microbiome analyses of blood and tissues suggest cancer diagnostic approachNature3/1/20200SB-CGC
Screening TCGA database for prognostic genes in lower grade glioma microenvironmentAnn Transl Med3/1/2020GDC
Genomic Characterization of Non-Invasive Differentiated-Type Gastric Cancer in the Japanese PopulationCancers (Basel)2/22/2020GDC
Proteogenomic Characterization of Endometrial CarcinomaCell2/20/2020PDC
The Pan-Cancer Landscape of Prognostic Germline Variants in 10,582 PatientsGenome Medicine2/17/2020SB-CGC
Immunogenomic Pathways Associated with Cytotoxic Lymphocyte Infiltration and Survival in Colorectal CancerBMC Cancer2/14/2020Broad - FireCloud 
The Angiosarcoma Project: Enabling Genomic And Clinical Discoveries In A Rare Cancer Through Patient-Partnered Research Nature Medicine2/10/2020GDC
Steroid Enzyme and Receptor Expression and Regulations in Breast Tumor Samples - A Statistical Evaluation of Public DataJ Steroid Biochem Mol Biol2/1/2020GDC
Loss of Kat2a Enhances Transcriptional Noise and Depletes Acute Myeloid Leukemia Stem-Like CellseLife1/27/2020SB-CGC
Microscaled Proteogenomic Methods For Precision Oncology Nature Communications1/27/2020PDC
Knowledge-Guided Analysis of “Omics” Data Using the KnowEnG Cloud PlatformPLoS1/23/2020SB-CGC
Screening the Cancer Genome Atlas Database for Genes of Prognostic Value in Acute Myeloid LeukemiaFront Oncol1/21/2020GDC
Discovering the Anticancer Potential of Non-Oncology Drugs by Systematic Viability ProfilingNature Cancer1/20/2020Broad - FireCloud 
A Protein‐Centric Approach for Exome Variant Aggregation Enables Sensitive Association Analysis with Clinical OutcomesHuman Mutation1/12/2020ISB-CGC
Building Containerized Workflows Using the BioDepot-Workflow-BuilderCell Systems11/27/2019SB-CGC
Identification And Analyses Of Extra-Cranial And Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors With Cytotoxic T Cell Infiltration Cell Reports11/19/2019GDC
Genomic Profiling Of Childhood Tumor Patient-Derived Xenograft Models To Enable Rational Clinical Trial Design Cell Reports11/5/2019GDC
Integrated Proteogenomic Characterization of Clear Cell Renal Cell CarcinomaCell10/31/2019PDC
Somatic Truth Data from Cell LineagebioRxiv10/31/2019Broad - FireCloud 
Cumulus: a cloud-based data analysis framework for large-scale single-cell and single-nucleus RNA-seqbioRxiv10/30/2019Broad - FireCloud 
Identifying Epigenetic Signature of Breast Cancer with Machine Learning arXiv10/12/2019ISB-CGC
CellBender remove-background: a deep generative model for unsupervised removal of background noise from scRNA-seq datasetsbioRxiv10/3/2019Broad - FireCloud 
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular CarcinomaCell10/3/2019PDC
Improved detection of gene fusions by applying statistical methods reveals oncogenic RNA cancer driversPNAS7/30/2019SB-CGC
Clonal replacement of tumor-specific T cells following PD-1 blockadeNature Medicine7/29/2019Broad - FireCloud 
A cytosine deaminase for programmable single-base RNA editingScience7/26/2019Broad - FireCloud 
Before And After: A Comparison Of Legacy And Harmonized TCGA Data At The Genomic Data Commons Cell Systems7/24/2019GDC
Read Mapping and Transcript Assembly: A Scalable and High-Throughput Workflow for the Processing and Analysis of Ribonucleic Acid Sequencing DataFrontiers in Genetics6/24/2019SB-CGC
Achieving reproducibility and accuracy in cancer mutation detection with whole-genome and whole-exome sequencingbioRxiv6/2/2019SB-CGC
Proteogenomic Analysis Of Human Colon Cancer Reveals New Therapeutic Opportunities Cell5/2/2019PDC
SNP2SIM: a modular workflow for standardizing molecular simulation and functional analysis of protein variantsBMC Bioinformatics 5/1/2019SB-CGC
The Germline Variants rs61757955 and rs34988193 Are Predictive of Survival in Lower Grade Glioma PatientsMolecular Cancer Research 5/1/2019SB-CGC
Building Portable and Reproducible Cancer Informatics Workflows: An RNA Sequencing Case StudyMethods Mol Biol4/1/2019SB-CGC
Genome-Wide Discovery Of Somatic Coding And Non-Coding Mutations In Pediatric Endemic And Sporadic Burkitt Lymphoma Blood3/21/2019GDC
Genetic Mechanisms Of Primary Chemotherapy Resistance In Pediatric Acute Myeloid Leukemia Leukemia2/13/2019GDC
Data Lakes, Clouds and Commons: A Review of Platforms for Analyzing and Sharing Genomic DataTrends in Genetics1/25/2019DCF
Pregnancy-Associated Plasma Protein-A (PAPP-A) in Ewing Sarcoma: Role in Tumor Growth and Immune EvasionJNCI1/20/2019ISB-CGC
Clinical Resistance To Crenolanib In Acute Myeloid Leukemia Due To Diverse Molecular Mechanisms Nature Communications1/16/2019GDC
Proteogenomic Characterization of Human Early-Onset Gastric Cancer.Cancer Cell1/14/2019PDC
Proteogenomic Characterization Of Human Early-Onset Gastric Cancer Cancer Cell1/14/2019PDC
Structural Differences Between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target RepertoiresCell Reports1/8/2019SB-CGC
restfulSE: A semantically rich interface for cloud-scale genomics with BioconductorF1000 Research1/7/2019ISB-CGC
Maximizing the Utility of Cancer Transcriptomic DataTrends in Cancer Research12/4/2018SB-CGC
Personal Genome Project UK (PGP-UK): a research and citizen science hybrid project in support of personalized medicineBMC Med Genomics11/27/2018SB-CGC
Lack of detectable neoantigen depletion in the untreated cancer genomebioRxiv11/26/2018Broad - FireCloud 
Clinically Relevant Cytotoxic Immune Cell Signatures And Clonal Expansion Of T-Cell Receptors In High-Risk Mycn-Not-Amplified Human Neuroblastoma Clinical Cancer Research11/15/2018GDC
Association analysis using somatic mutationsPLOS Genetics11/2/2018SB-CGC
The Chromatin Accessibility Landscape Of Primary Human Cancers Science10/26/2018GDC
Functional Genomic Landscape Of Acute Myeloid Leukaemia Nature10/17/2018GDC
Integrative Molecular Characterization Of Malignant Pleural Mesothelioma Cancer Discovery10/15/2018GDC
QuagmiR: a cloud-based application for isomiR big data analyticsBioinformatics10/9/2018SB-CGC
Using Semantic Web Technologies to Enable Cancer Genomics Discovery at Petabyte ScaleCancer Informatics9/28/2018SB-CGC
The Genetic Basis And Cell Of Origin Of Mixed Phenotype Acute Leukaemia Nature9/12/2018GDC
Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker DiscoveryBiomarkers for Immunotherapy of Cancer9/10/2018ISB-CGC
Proteomics, Post-Translational Modifications, And Integrative Analyses Reveal Molecular Heterogeneity Within Medulloblastoma Subgroups Cancer Cell9/10/2018PDC
Identification of rare-disease genes in diverse undiagnosed cases using whole blood transcriptome sequencing and large control cohortsbioRxiv9/4/2018Broad - FireCloud 
Data Harmonization for a Molecularly Driven Health SystemCell8/23/2018DCF
Comprehensive Analysis Of AlteRNAtive Splicing Across Tumors From 8,705 Patients Cancer Cell8/13/2018GDC
Recurrent Tumor-Specific Regulation of Alternative Polyadenylation of Cancer-Related GenesBMC Genomics7/13/2018ISB-CGC
Reproducible Workflow For Multiplexed Deep-Scale Proteome And Phosphoproteome Analysis Of Tumor Tissues By Liquid Chromatography-Mass Spectrometry Nature Protocols7/1/2018PDC
Evaluation Of NCI-7 Cell Line Panel As A Reference Material For Clinical Proteomics Journal of Proteome Research6/1/2018PDC
Progress Towards Cancer Data EcosystemsCancer J5/30/2018DCF
Mass Spectrometry-Based Proteomics Reveals Potential Roles Of Nek9 And Map2K4 In Resistance To Pi3K Inhibition In Triple-Negative Breast Cancers Cancer Research5/15/2018PDC
The Immune Landscape of Cancer Immunity4/17/2018ISB-CGC, SB-CGC
Genetics And Pathogenesis Of Diffuse Large B Cell Lymphoma New England Journal of Medicine4/12/2018GDC
A Comprehensive Pan-Cancer Molecular Study Of Gynecologic And Breast Cancers Cancer Cell4/9/2018GDC
Comparative Molecular Analysis Of Gastrointestinal Adenocarcinomas Cancer Cell4/9/2018GDC
Genomic And Functional Approaches To Understanding Cancer Aneuploidy Cancer Cell4/9/2018GDC
A Pan-Cancer Analysis Of Enhancer Expression In Nearly 9000 Patient Samples Cell4/5/2018GDC
An Integrated TCGA Pan-Cancer Clinical Data Resource To Drive High Quality Survival Outcome Analytics Cell4/5/2018GDC
Cell-Of-Origin Patterns Dominate The Molecular Classification Of 10,000 Tumors From 33 Types Of Cancer Cell4/5/2018GDC
Comprehensive Characterization Of Cancer Driver Genes And Mutations Cell4/5/2018GDC
Machine Learning Identifies Stemness Features Associated With Oncogenic Dedifferentiation Cell4/5/2018GDC
Oncogenic Signaling Pathways In The Cancer Genome Atlas Cell4/5/2018GDC
Pathogenic Germline Variants In 10,389 Adult Cancers Cell4/5/2018GDC
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology ImagesCell Reports4/3/2018ISB-CGC
Genomic And Molecular Landscape Of DNA Damage Repair Deficiency Across The Cancer Genome Atlas Cell Reports4/3/2018GDC
Genomic, Pathway Network, And Immunologic Features Distinguishing Squamous Carcinomas Cell Reports4/3/2018GDC
Integrated Genomic Analysis Of The Ubiquitin Pathway Across Cancer Types Cell Reports4/3/2018GDC
Machine Learning Detects Pan-Cancer Ras Pathway Activation In The Cancer Genome Atlas Cell Reports4/3/2018GDC
Molecular Characterization And Clinical Relevance Of Metabolic Expression Subtypes In Human Cancers Cell Reports4/3/2018GDC
Pan-Cancer Analysis Of LncRNA Regulation Supports Their Targeting Of Cancer Genes In Each Tumor Context Cell Reports4/3/2018GDC
Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines Cell Systems3/28/2018ISB-CGC
Pan-Cancer Alterations Of The Myc Oncogene And Its Proximal Network Across The Cancer Genome Atlas Cell Systems3/28/2018GDC
Pan-Cancer Genome And Transcriptome Analyses Of 1699 Paediatric Leukaemias And Solid Tumours Nature3/15/2018GDC
The Integrated Genomic Landscape Of Thymic Epithelial Tumors Cancer Cell2/12/2018GDC
Genomics In Childhood Acute Myeloid Leukemia Comes Of Age Nature Medicine1/9/2018GDC
The Molecular Landscape Of Pediatric Acute Myeloid Leukemia Reveals Recurrent Structural Alterations And Age-Specific Mutational Interactions Nature Medicine12/11/2017GDC
MicroRNA Expression-Based Model Indicates Event-Free Survival In Pediatric Acute Myeloid Leukemia Journal of Clinical Oncology12/10/2017GDC
Using the Seven Bridges Cancer Genomics Cloud to access and analyze petabytes of cancer data Current Protocols in Bioinformatics12/8/2017SB-CGC
Comprehensive And Integrated Genomic Characterization Of Adult Soft Tissue Sarcomas Cell11/2/2017GDC
The Cancer Genomics Cloud: Collaborative, reproducible, and democratized—a new paradigm in large-scale computational research Cancer Research11/1/2017SB-CGC
The ISB Cancer Genomic Cloud: A Flexible Cloud-Based Platform for Cancer Genomic Research Cancer Research11/1/2017ISB-CGC
Comprehensive Molecular Characterization Of Muscle-Invasive Bladder Cancer Cell10/19/2017GDC
A Comprehensive Infrastructure for Big Data in Cancer Research: Accelerating Cancer Research and Precision MedicineFront Cell Dev Biol.9/21/2017NCI
APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphismNat Commun.9/6/2017PDC
A Children's Oncology Group And Target Initiative Exploring The Genetic Landscape Of Wilms Tumor Nature Genetics8/21/2017GDC
Precise, pan-cancer discovery of gene fusions reveals a signature of selection in primary tumorsbioRxiv8/18/2017SB-CGC
Integrated Genomic Characterization Of Pancreatic Ductal Adenocarcinoma Cancer Cell8/14/2017GDC
Integrative Analysis Identifies Four Molecular And Clinical Subsets In Uveal Melanoma Cancer Cell8/14/2017GDC
The NCI Genomic Data Commons As An Engine For Precision Medicine Blood7/27/2017GDC
The Genomic Landscape Of Pediatric And Young Adult T-Lineage Acute Lymphoblastic Leukemia Nature Genetics7/3/2017GDC
Integrative Genomic Analysis Of Cholangiocarcinoma Identifies Distinct Idh-Mutant Molecular Profiles Cell Reports6/27/2017GDC
Comprehensive And Integrative Genomic Characterization Of Hepatocellular Carcinoma Cell6/15/2017GDC
Biomarker Significance Of Plasma And Tumor Mir-21, Mir-221, And Mir-106A In Osteosarcoma Oncotarget5/27/2017GDC
Proteogenomic Integration Reveals Therapeutic Targets In Breast Cancer Xenografts Nature Communications3/28/2017PDC
Integrated Genomic And Molecular Characterization Of Cervical Cancer Nature3/16/2017GDC
Integrated Molecular Characterization Of Uterine Carcinosarcoma Cancer Cell3/13/2017GDC
Comprehensive Molecular Characterization Of Pheochromocytoma And Paraganglioma Cancer Cell2/13/2017GDC
Integrated Genomic Characterization Of Oesophageal Carcinoma Nature1/12/2017GDC
Significance Of Tp53 Mutation In Wilms Tumors With Diffuse Anaplasia: A Report From The Children'S Oncology Group Clinical Cancer Research11/15/2016GDC
Toward A Shared Vision For Cancer Genomic Data New England Journal of Medicine9/22/2016GDC
Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian CancerCell7/28/2016PDC
Csf3R Mutations Have A High Degree Of Overlap With Cebpa Mutations In Pediatric Aml Blood6/16/2016GDC
Proteogenomics Connects Somatic Mutations To Signalling In Breast Cancer Nature6/2/2016PDC
Proteogenomics Connects Somatic Mutations to Signalling in Breast Cancer.Nature5/25/2016PDC
Comprehensive Pan-Genomic Characterization Of Adrenocortical Carcinoma Cancer Cell5/9/2016GDC
Genomic Profiling Of Pediatric Acute Myeloid Leukemia Reveals A Changing Mutational Landscape From Disease Diagnosis To Relapse Cancer Res4/15/2016GDC
Genome-Wide Profiles Of Extra-Cranial Malignant Rhabdoid Tumors Reveal Heterogeneity And Dysregulated Developmental Pathways Cancer Cell3/14/2016GDC
Molecular Profiling Reveals Biologically Discrete Subsets And Pathways Of Progression In Diffuse Glioma Cell1/28/2016GDC
Comprehensive Molecular Characterization Of Papillary Renal Cell Carcinoma New England Journal of Medicine1/14/2016GDC
Genetic Predisposition To Neuroblastoma Mediated By A Lmo1 Super-Enhancer Polymorphism Nature12/17/2015GDC
Mllt1 Yeats Domain Mutations In Clinically Distinctive Favourable Histology Wilms Tumours Nature Communications12/4/2015GDC
The Molecular Taxonomy Of Primary Prostate Cancer Cell11/5/2015GDC
Comprehensive Molecular Portraits Of Invasive Lobular Breast Cancer Cell10/8/2015GDC
Proteomic analysis of colon and rectal carcinoma using standard and customized databasesScientific Data7/21/2015PDC
Tcf21 Hypermethylation In Genetically Quiescent Clear Cell Sarcoma Of The Kidney Oncotarget6/30/2015GDC
Relapsed Neuroblastomas Show Frequent Ras-Mapk Pathway Mutations Read The Full Article Nature Genetics6/29/2015GDC
Comprehensive And Integrative Genomic Characterization Of Diffuse Lower Grade Gliomas New England Journal of Medicine6/25/2015GDC
Genomic Classification Of Cutaneous Melanoma Cell6/18/2015GDC
Rise And Fall Of Subclones From Diagnosis To Relapse In Pediatric B-Acute Lymphoblastic Leukaemia Nature Communications3/19/2015GDC
Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome mapsNature Medicine3/2/2015PDC
Recurrent Dgcr8, Drosha, And Six Homeodomain Mutations In Favorable Histology Wilms Tumors Cancer Cell2/9/2015GDC
Comprehensive Genomic Characterization Of Head And Neck Squamous Cell Carcinomas Nature1/29/2015GDC
Integrated Genomic Characterization Of Papillary Thyroid Carcinoma Cell10/23/2014GDC
Comprehensive Molecular Characterization Of Gastric Adenocarcinoma Nature9/11/2014GDC
Targetable Kinase-Activating Lesions In Ph-Like Acute Lymphoblastic Leukemia New England Journal of Medicine9/11/2014GDC
The Somatic Genomic Landscape Of Chromophobe Renal Cell Carcinoma Cancer Cell9/8/2014GDC
Multiplatform Analysis Of 12 Cancer Types Reveals Molecular Classification Within And Across Tissues Of Origin Cell8/14/2014GDC
Comprehensive Molecular Profiling Of Lung Adenocarcinoma Nature7/31/2014GDC
Comprehensive Molecular Characterization Of Urothelial Bladder Carcinoma Nature3/20/2014GDC
The Somatic Genomic Landscape Of Glioblastoma Cell10/10/2013GDC
Mutational And Structural Analysis Of Diffuse Large B-Cell Lymphoma Using Whole-Genome SequeNCIng Blood8/15/2013GDC
Comprehensive Molecular Characterization Of Clear Cell Renal Cell Carcinoma Nature7/4/2013GDC
Genomic And Epigenomic Landscapes Of Adult De Novo Acute Myeloid Leukemia New England Journal of Medicine5/30/2013GDC
Analysis Of Foxo1 Mutations In Diffuse Large B-Cell Lymphoma Blood5/2/2013GDC
Integrated Genomic Characterization Of Endometrial Carcinoma Nature5/2/2013GDC
The Genetic Landscape Of High-Risk Neuroblastoma Nature Genetics1/20/2013GDC
Tyrosine Kinome SequeNCIng Of Pediatric Acute Lymphoblastic Leukemia: A Report From The Children'S Oncology Group Target Project Blood1/17/2013GDC
Prognostically Relevant Gene Signatures Of High-Grade Serous Ovarian Carcinoma The Journal of Clinical Investigation12/21/2012GDC
Comprehensive Molecular Portraits Of Human Breast Tumors Nature10/4/2012GDC
Comprehensive Genomic Characterization Of Squamous Cell Lung Cancers Nature9/27/2012GDC
Genetic Alterations Activating Kinase And Cytokine Receptor Signaling In High-Risk Acute Lymphoblastic Leukemia Cancer Cell8/14/2012GDC
Comprehensive Molecular Characterization Of Human Colon And Rectal Cancer Nature7/18/2012GDC
Tbl1Xr1/Tp63: A Novel Recurrent Gene Fusion In B-Cell Non-Hodgkin Lymphoma Blood5/24/2012GDC
The Molecular Genetic Makeup Of Acute Lymphoblastic Leukemia Hematology: American Society of Hematology Education Program1/1/2012GDC
Key Pathways Are Frequently Mutated In High-Risk Childhood Acute Lymphoblastic Leukemia: A Report From The Children'S Oncology Group Blood9/15/2011GDC
Frequent Mutation Of Histone-Modifying Genes In Non-Hodgkin Lymphoma Nature7/27/2011GDC
Integrated Genomic Analyses Of Ovarian Carcinoma Nature6/29/2011GDC
Ancestry And Pharmacogenomics Of Relapse In Acute Lymphoblastic Leukemia Nature Genetics2/6/2011GDC
Identification Of Novel Cluster Groups In Pediatric High-Risk B-Precursor Acute Lymphoblastic Leukemia With Gene Expression Profiling: Correlation With Genome-Wide DNA Copy Number Alterations, Clinical Characteristics, And Outcome Blood12/2/2010GDC
Rearrangement Of Crlf2 Is Associated With Mutation Of Jak Kinases, Alteration Of Ikzf1, Hispanic/Latino Ethnicity, And A Poor Outcome In Pediatric B-Progenitor Acute Lymphoblastic Leukemia Blood7/1/2010GDC
Identification Of A Cpg Island Methylator Phenotype That Defines A Distinct Subgroup Of Glioma Cancer Cell5/18/2010GDC
Gene Expression Classifiers For Relapse-Free Survival And Minimal Residual Disease Improve Risk Classification And Outcome Prediction In Pediatric B-Precursor Acute Lymphoblastic Leukemia Blood2/18/2010GDC
An Integrated Genomic Analysis Identifies Clinically Relevant Subtypes Of Glioblastoma Characterized By Abnormalities In Pdgfra, Idh1, Egfr And Nf1 Cancer Cell1/19/2010GDC
Somatic Mutations Altering Ezh2 (Tyr641) In Follicular And Diffuse Large B-Cell Lymphomas Of Germinal-Center Origin Nature Genetics1/17/2010GDC
Jak Mutations In High-Risk Childhood Acute Lymphoblastic Leukemia Proceedings of the National Academy of Sciences of the United States of America6/9/2009GDC
Deletion Of Ikzf1 And Prognosis In Acute Lymphoblastic Leukemia New England Journal of Medicine1/29/2009GDC
Comprehensive Genomic Characterization Defines Human Glioblastoma Genes And Core Pathways Nature10/23/2008GDC