CRDC is NCI’s primary data science platform, housing data from large NCI-funded programs and projects, including The Cancer Genome Atlas (TCGA), the Clinical Proteomic Tumor Analysis Consortium (CPTAC), and Human Tumor Atlas Network (HTAN), among others.
Researchers can make a data submission request of any one of CRDC's data commons, and the request will be considered, subject to each data common's governance guidelines.
Below find brief information about the types of data each considers, as well as links or contact information for data submission requests. Further below are more detailed descriptions.
|Data Commons / Website||Type of Data||Contact|
|Genomic Data Commons (GDC)||
Harmonized genomic data
Mass spectrometry data
Radiology, Digital Pathology, Cellular Imaging, etc.
Genomic, Genotyping array data, clinical trial data, etc. from canine studies
Genomic: Non-harmonized data
Proteomic: Reverse-phase protein arrays, etc.
Other types of cancer research data: See notes below.
If your cancer research data do not meet the above categorization, please contact the CRDC helpdesk at NCICRDC@mail.nih.gov
Learn More About the CRDC Data Commons
The following are currently accessible within the CRDC.
Genomic Data Commons
The Genomic Data Commons (GDC) is a unified data commons for genomic, clinical, and biospecimen data from cancer research programs. The GDC includes data from The Cancer Genome Atlas (TCGA), its pediatric equivalent, the Therapeutically Applicable Research to Generate Effective Treatments (TARGET) program, Foundation Medicine (FMI), the Cancer Cell Line Encyclopedia (CCLE), and a growing number of other sources.
Proteomic Data Commons
The Proteomic Data Commons (PDC) offers access to highly curated and standardized biospecimen, clinical, and proteomic data. The PDC includes data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) program and will grow to include other sources over time. The data are open access and can be browsed interactively using a series of filters and are accessed with an API.
Imaging Data Commons
The Imaging Data Commons (IDC) provides cloud-based access to a wide variety of imaging data sets from The Cancer Imaging Archive and other NCI projects. Its connection to a wide variety of analytical tools allows researchers and data scientists to train and explore imaging models without downloading data.
Integrated Canine Data Commons
The Integrated Canine Data Commons (ICDC) includes clinical, biospecimen, genomics, proteomics, and imaging data from naturally occurring cancer in canine cancer patients. Researchers can explore multiple types and collections of open-access data directly through the portal or through one of NCI's Cloud Resources.
Cancer Data Service
The Cancer Data Service (CDS) is for cancer research data generated by NCI-funded programs that do not meet the submission criteria for a specific CRDC data commons. The CDS is for:
- data that do not meet the minimum metadata standards for submission to another CRDC data commons,
- studies that are on a waiting list for submission to a specific CRDC data commons (e.g., GDC), and
- studies that are in progress and need a place to store and analyze data during the acquisition phase.